We are a TechBio company mapping the extremes of biology.
Biology is the most powerful manufacturing technology on Earth. We build the computational infrastructure to program it for the harshest industrial constraints.
Nature's archive is vast.
Industry's tools are limited.
For billions of years, evolution has engineered proteins capable of surviving boiling acid, deep-sea pressure, and arctic ice.
Yet modern manufacturing still relies on toxic petrochemicals because discovering these natural biological machines using traditional wet-lab methods is too slow, too expensive, and relies entirely on blind luck.
Engineering biology through physics.
Dennett Labs replaces trial-and-error with computation.
Our platform, CRANE, uses physics-informed AI to simulate how millions of unmapped protein sequences will fold and behave under extreme thermal and chemical stress. We don't guess. We compute the exact molecular machines required to power sustainable industry.
A crane, not a skyhook
The name is a deliberate nod to Daniel Dennett's concept from Darwin's Dangerous Idea. A crane is a grounded, algorithmic process that builds complex design from the bottom up—as opposed to a “skyhook,” which relies on magic.
CRANE does exactly this: it builds functional, predictive insight from raw biological data. No magic. Just physics and computation.