Programmable
Biology
Nature already built the enzyme you need. We use AI to find it, test it, and hand you a ranked shortlist—before you spend a single dollar in the lab.
Meet CRANE
Three billion years of evolution, compressed into 300 milliseconds.
CRANE (Candidate Ranking for Adaptive Novel Enzymes) leverages the DNA of extremophiles—organisms thriving in boiling acid springs and frozen tundras—to solve complex industrial chemistry problems.
By mapping the known protein universe against specific thermal and pH stressors, our physics-informed neural networks accurately simulate how these wild enzymes will fold, bind, and perform in extreme, real-world environments.
Bacillus subtilis AprB Protease Simulation
Evaluating 10,000 extremophile sequences against pH 10.5 & 65°C thermal stress.
A computational funnel that finds the needle.
Sequence Sourcing & Filtering
We source biological data from Earth's most resilient organisms. We instantly filter out candidates that cannot be manufactured or scaled in commercial production.
Evolutionary Stability Test
We check each candidate against the mathematical rules of natural protein structure to ensure it is stable, reliable, and functional.
Environmental Stress Simulation
We test top candidates in a digital environment set to your exact operating conditions. We expose the protein to a wide spectrum of industrial stress—verifying whether its chemical structure holds firm or breaks down.
Actionable Shortlist Delivery
We score every candidate on resilience and catalytic performance, delivering a clean, prioritized shortlist ready for laboratory synthesis.
The solutions already exist.
We just have to compute them.
Nature has already engineered proteins capable of surviving Earth's most extreme environments. We use advanced AI to search this massive genetic archive and compute the exact catalysts that will transform your manufacturing process.
You define the constraints.
We compute the biology.
Industrial Verticals
Laundry & Dish Detergents
Lysine deprotonation mitigation via Arginine salt-bridge stabilization.
Ready to discover your next industrial catalyst?
Input your target temperature, pH, and manufacturing constraints. The CRANE platform instantly computes a verified shortlist of natural enzymes ready for your process.